On September 28, 1998, 24 hours prior to the events of Resident Evil 2, former Special Tactics And Rescue Service (S.T.A.R.S.) member Jill Valentine attempts to escape from Raccoon City. Most of the population has been transformed into zombies by an outbreak of the T-virus, a new type of biological weapon secretly developed by the pharmaceutical company Umbrella. On her way to the Raccoon City Police Department, Jill runs into fellow team member Brad Vickers, who is later killed by a new enemy. This creature, Nemesis-T Type, is a bio-organic weapon programmed to target the remaining surviving S.T.A.R.S. members, who witness Umbrella’s experiments. As she evades Nemesis, Jill encounters three surviving members of the Umbrella Biohazard Countermeasure Service (U.B.C.S.): Carlos Oliveira, Mikhail Victor, and Nikolai Zinoviev. Nikolai explains to Jill and Carlos that a rescue helicopter can be contacted if they manage to reach the city’s Clock Tower to ring the bell.
As they make their way to the clock tower, Nikolai was proclaimed presumed dead, but Nemesis corners the remaining members of the group onto the cable car as they headed to the tower. as Mikhail would sacrifice himself with a grenade, causing the car to crash into the tower’s central courtyard and separating Jill and Carlos briefly. At the Clock Tower, Jill summons the helicopter by ringing the Clock Tower’s bell before being confronted by Nemesis, which destroys the helicopter and infects Jill with the T-virus. Jill manages to temporarily defeat Nemesis but she would fall unconscious due to the T-virus infection given by Nemesis. as Carlos finds Jill and takes her to safety within the Clock Tower. Three days later, he finds a vaccine for Jill’s T-virus infection in a nearby hospital. He then returns and administers it to Jill, saving her.
After she regains consciousness, Jill proceeds towards the Raccoon Park and enters the park caretaker’s cabin. There, she runs into Nikolai, who reveals that he is a “supervisor” sent into Raccoon City to gather combat data on Umbrella’s bioweapons. Nikolai retreats, and Jill later is confronted by Gravedigger which is a massive worm-like creature. as Jill defeats the monster and escapes to an abandoned factory at the rear of the park. Inside the factory, Jill meets up with Carlos, who tells her that the U.S. government is planning to launch a nuclear missile into Raccoon City to eradicate the T-virus infestation. After confronting Nemesis and grabbing a keycard needed to escape, Jill learns from the factory’s control tower that the missile attack on Raccoon City has begun, with only a short time left before the city is destroyed.
Depending on the path taken by the player, Jill’s final encounter with Nikolai will differ. In one version of the events, Nikolai will attempt to start a gunfight with Jill, only to be taken by surprise by Nemesis and killed. In another event, Nikolai will hijack Jill’s intended escape chopper, and the player must either reason with Nikolai or destroy the helicopter. If Jill negotiates with Nikolai, he reveals that he has killed the other supervisors and boasts about collecting the bounty placed on Jill by Umbrella before escaping. Regardless of Nikolai’s fate, Jill makes her way to the rear yard and confronts Nemesis one last time. After an intense battle, Jill defeats Nemesis with the help of a large prototype railgun before meeting up with Carlos and escaping the city via a helicopter. If the previous escape chopper was stolen by Nikolai, Jill, and Carlos will instead meet up with S.T.A.R.S. Alpha Team’s weapons specialist Barry Burton, who helps them escape in his helicopter. The nuclear missile vaporizes Raccoon City, and Jill swears revenge on Umbrella. A newscast then briefly details the destruction and offers condolences for the lost lives.
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