A team of American researchers has discovered that female “Aedes aegypti”
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A question that we ask each other every summer, in vain: why is it so difficult, even impossible, escape from the ruthless detection of mosquitoes? Often accompanied by another question: why do they bite me more than everyone else? Scientists and repellent insect manufacturers have known for some time that carbon dioxide, exhaled when breathing and octanol, a volatile compound present in sweat, form airborne roads that mosquitoes use to take them to their victims. What scientists did not know, but now they have discovered, is that mosquitoes, unlike other creatures in the animal kingdom, have multiple smell and flavor receptors in each of their thousands of olfactory neurons. In 2004, researchers Richard Axel and Linda Buck won the Nobel Prize in Medicine for discoveries related to “Odorant Receptors and the Organization of the Olfative System.” A decade before, Axel and Buck had discovered that there are approximately 1,000 genes involved in the smell process, which are responsible for a similar number of olfactory receptors. His work also showed that each olfactory sensory neuron expresses only one of these receptors, a phenomenon called “a neuron -uno -receptor”, and that this information is sent as an electrical signal to the olfactory bulb, the part of the brain of the brain of The mammals that processes and interprets aromas. But according to Leslie Vosshall, head of the Neurogenetic and Behavior Laboratory at Rockefeller University in New York and a ex postdoc in the Axel laboratory, “mosquitoes threw all the rules of Buck and Axel in the garbage can.” Vosshall directs a research program aimed at understanding the olfactory mosquito system. Specifically, his work focuses on the kind of Aedes Aegypti mosquito, commonly known as the “Dengue mosquito” for his role in the propagation of the virus that causes dengue fever. But Aedes Aegypti is not only responsible for transmitting dengue: its bites can also introduce pathogens that cause yellow fever, chikungunya, zika and Mayaro virus disease. Discover how to block the smell receptors of Aedes Aegypti females, which bite, could have important implications for global health and disease prevention. Detail of the mosquito antenna ‘Aedes aegypti’, as seen under an electronic microscope. The fluorescent green corresponds to the dyed olfactory neurons using the CRISPR technique. Margo Herre
The last findings of Vosshall’s investigation and his colleagues, The Scientific Journal Cell, show that Mosquitoe
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