Medication Shelf Life in Space & Down Here!
00:00 Introduction
00:36 Effects of Space flight
00:45 Is Space Safe?
00:57 Can we use ISS data here?
01:02 The 5 ISS Kits
01:35 Can you use expired meds?
01:59 How many meds do astronauts take?
02:59 EIMO
03:22 What lessons for Earth from the ISS?
04:19 SLEP & the LAW!
04:46 Canada in Space
05:19 ISS Meds
06:40 History of USA Space Medicine
08:51 ISS Shelf Life
09:20 Making sterile water
09:38 SLEP Data
11:01 ISS Shelf Life for 111 meds
12:22 Kaplan-Meier Curve
12:33 When do antibiotics expire?
13:23 Conclusion
13:57 Wolfie Terrier in Space
References
https://www.goodrx.com/trimethobenzamide/what-is
Clinical Pharmacology of Spaceflight
https://www.medscape.com/viewarticle/735035_3?form=fpf
Wringing out Water on the ISS – for Science!
https://www.youtube.com/watch?v=o8TssbmY-GM
https://www.space.com/24701-how-long-does-it-take-to-get-to-mars.html
https://www.spacesafetymagazine.com/spaceflight/space-medicine/evolution-medical-kits-mercury-iss/
https://www.nasa.gov/image-article/medical-kits-iss/
https://www.fda.gov/drugs/pharmaceutical-quality-resources/expiration-dates-questions-and-answers
Supplying a pharmacy for NASA exploration spaceflight: challenges and current understanding
https://www.nature.com/articles/s41526-019-0075-2
When do prescription medications REALLY expire?
https://www.youtube.com/watch?v=3SWvfXq3Bc4
Expiration analysis of the International Space Station formulary for exploration mission planning
https://www.nature.com/articles/s41526-024-00414-3
Consider joining the Huples Kittens!
https://www.youtube.com/channel/UCVG2d2L-0kF6w-H7IlkXZ2Q/join
#space #ISS #shelflife #expiry
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It's all about that Space.. that Space.. no Trebbel
This has been really on my mind. I want to vac seal some meds….
Thank you HUPLES. I will continue to drop your name as long as Kitty cameo. Peace
Like 1
Watched the video, HC
H.C. I remember a study the U.S. Navy did in the early 2005. Antibiotics from 1965 was still 95% effective 40 years after their manufacture.
As for which antibiotics. I don't know. Long live Emperor Wolfie. Cheers, Mate.
"after 5 years the medications are no longer deemed to be safe for human use" then I remember the US Military asked the FDA to do a review of meds, the report shows that most medications are good for at least 15 years (except a very few outliers) beyond expiration dates..(is this the SLEP you referred to??) ..so you can see why i'm confused here. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7040264/
Interesting. I wonder why drugs degenerate more quickly in space. I do have a couple of issues. My understanding g is that modern doxycycline is stable and does not have the decomposition problems of old tetracycline. It would not be poisonous. Asprin that smells of vinegar is breaking down into acetic acid and salicylic acid. The salicylic acid is generally a low dose and would not hurt adults. I would agree it is not doing anything good for you, but the dosage would be less than poisonous (I am still alive, but don't general use asprin now).
Per the usual, an excellent video chronicling; your/other’s knowledge, work ethic, and time invested to help us become more properly informed 👍🏼 Excellent too as it as another spoke in the wheel that highlights how the MUSKY one is an untrustworthy, King of bread and circuses, full of; devious intent, narcissism, greed, and lust for power.
I took Modafinil for a year to combat lethargy along with Effexor for depression. Boosted my I.Q. and worked great until it sent my blood pressure skyrocketing.
Interesting video Huples! Did I hear you correctly that liquid antibiotics are more shelf-stable than tablet (or powder) form antibiotics? I thought it was the other way 'round – or is it just non-antibiotic medications that are more shelf-stable in their dry form?
This is great information if you're bugging out in space 😂, in a real long term SHTF, medical herbalist will be rock stars.
Good video. I will usually use meds that are two years past expiration. I have had no issues and they seemed to work.
🤙🐑🤙
I would not have thought allergies would have been a problem in space.
"Typically, drug manufacturers test their products’ stability at two to three years out. The drug might be stable beyond that time, but it isn’t tested for a number of reasons because:
This is viewed as an acceptable time frame.
It eliminates the manufacturers’ need to perform long-term stability tests.
It requires pharmacies and consumers to replace expired products.
Stability studies have shown that the actual shelf life of medications might extend longer than the expiration dates indicate. But after a drug leaves the manufacturer, there’s no guaranteed consistency of proper storage, which can affect its safety and potency."
I have taken vinegary-smelling aspirin many times with no ill effects. ( That was before I ever heard that it's toxic. Ignorance is bliss. )
Bang Bang 🌞🌞🌞
The Mars travel aspect is very interesting.
Always sticks in my mind about the Aspirin (after one of your previous videos).
I try to keep things as current as possible out to a max of 2 years after expiry in order to have as much of a time frame of longevity as possible.