Dead Space 3 is set in 2514. After the events of Dead Space, EarthGov captured Isaac Clarke and harvested his mind for Marker blueprints in order to revive the Marker program, in which Markers are used to provide resources and power for the Human race. The Marker built by a delirious Isaac on Titan Station somehow “activated”, resulting in another outbreak of Necromorphs. Isaac then escaped with mining engineer Ellie Langford after he destroyed the Marker, resulting in Titan Station’s destruction.
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