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Petri dishes contaminated with the wrong cell lines have compromised thousands of studies, leaving us with questionable treatments for a variety of diseases. How do we solve this enormous, microscopic problem?
Hosted by: Hank Green (he/him)
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source
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1/3rd of all commercially used cell lines “is/are” contaminated with cell lines not of the expected subject base. I see! “That’s quite different, isn’t it!” ~ Emily Littell
#ICLAC has identified 535 individual cell lines purporting to be “pure”, yet alas … Are “contaminated” clones of an entirely different type of cell line unworthy of receiving the targeted research protocols. “My goodness! This is worse than the #AIDs contaminated plasma of yesteryear that was drawn from the needled arms of `heroin – tuberculosis` sufferers living on the streets of San Francisco back in the 2010’s …!” ~ Gavin Newsome
“Where do we go from here! When all of the children are grown up?” ~ Alan Parsons
“Used pipettes!” … Dip one, Dip two! No different than when that worker in Philadelphia sliced that watermelon with an already used knife that was previously slicing a slab of uncooked raw meat! Now, that’s how you transfer pathogens onto the buffet at an American Legion get-together! The result of THAT “experiment” was to enact a law requiring all “food handlers” to obtain a license after passing an exam on food safety. What are the lab-workers licensed to do other than helping to generate false reports that #BigPharma can then shove in front of the #DEA to declare efficacy over and above a standard placebo double-blind trial?
Wow Hanks most based show, doesn’t he know that the science is settled and unquestionable?
Incredibly important and well-done presentation. Every biological and pharmaceutical lab professor should have their students and apprentices watch it.
important news that needs more attention
Finally, a SciShow video on this topic. It's good to see up to date information on the actual numbers of suspected contaminated samples. I've also never really understood how cell samples got contaminated – when I first learnt about the issue, it implied that even the cells inside a person's body could be infected by this miasma of lab cells. Horrible to contemplate – and not exactly scientifically sound. This was a quick, simple and great explanation of how cell line contamination happens.
I gained nothing from this video
My anxiety is climbing.
I’m sure someone already posted this but be sure to always “Trust The Science”!
Wait, this isn't journey to the microcosmos
Okay but trust the science bro.
Wow there is A LOT of drug selling bots spamming in the comments. I dont think this needs to be said but dont buy drugs from Youtube comment section. Its hard to believe anyone is desperate enough to buy anything from these bots. Although if you are stupid enough to do it you propably deserve it.
Linode is a pretty cursed name. look it up.
I hear that's how they make Taco Bell meat. 🌮 🔔 🍖
I understand that it's the researcher's responsibility, but what about the responsibility of the people selling these? Should contaminated cell lines even be sold?
Thank you for acknowledging Henrietta!
I see a zombie movie script in this video.
Thanks for the video, this was really fascinating!
Cancer severed up on a plate
@ 12:44 access it all around the world you say? Even North Korea, does this include North Korea?
I take issue with "Researches are rarely required to prove that their cell lines are the ones they think they are." In the past few years, many of the big journals (more than just Nature owned journals) require short tandem repeat (STR) profiling of all new deposited cell lines as well as your own validation of the cell line you claim you're working with. Same with common microbial contaminants. Source: have performed a LOT of STR profiling and contamination testing on cell lines before submitting manuscripts for publication.
virally transmissible cancer is like my favorite disease, it's just so cool
I think labeling all cells as their DNA code reference rather than using common terms would help. I know human brains don’t work super well with that until they adapt, but it would keep problems clear in the future as well as lock in the exact nature of the cell. Even if one day it needs to be rebuilt from scratch to match the code. This would also allow similar genetic codes to be easily identified by checking their barcode basically.
We read The Immortal Life of Henrietta Lacks for summer reading during high school one year, it's a great book and definitely worth the read!!!!!!!!!!!
Judy mikovits has been screaming this for years and years
Teenagers and their ridiculous layer choices
All of our studies are garbage